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K Irie Selected Research

indolactam V

3/2001The amide hydrogen of (-)-indolactam-V and benzolactam-V8's plays a critical role in protein kinase C binding and tumor-promoting activities.
9/2000Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V.

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K Irie Research Topics

Disease

7Neoplasms (Cancer)
11/2001 - 02/2000
4Aneurysm (Aneurysms)
04/2014 - 09/2002
4Periodontitis
04/2013 - 05/2008
2Thrombosis (Thrombus)
04/2014 - 09/2003
2Alzheimer Disease (Alzheimer's Disease)
09/2011 - 10/2007
2Bone Resorption
10/2001 - 07/2000
2Chronic Hepatitis C
05/2001 - 01/2000
1Body Weight (Weight, Body)
04/2014
1Amyloid angiopathy
11/2012
1Cerebral Hemorrhage
11/2012
1Dementia (Dementias)
11/2012
1Hypertension (High Blood Pressure)
11/2010
1Inflammation (Inflammations)
05/2008
1Periodontal Diseases (Periodontal Disease)
05/2008
1Catalepsy
01/2008
1Amyloid Plaque
10/2007
1Heart Failure
05/2006
1Hypothermia
03/2003
1Spontaneous Remission
11/2001
1Carcinoma (Carcinomatosis)
10/2001
1Hepatocellular Carcinoma (Hepatoma)
09/2001
1Glioma (Gliomas)
07/2001
1Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
05/2001
1Osteosarcoma (Osteogenic Sarcoma)
04/2001
1Ischemia
12/2000
1Embryonal Carcinoma
10/2000
1Myeloid Sarcoma (Chloroma)
09/2000
1Ischemic Stroke
07/2000
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
07/2000
1Necrosis
07/2000
1Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/2000
1Polyarteritis Nodosa (Periarteritis Nodosa)
01/2000

Drug/Important Bio-Agent (IBA)

2CollagenIBA
04/2013 - 04/2012
2Peptides (Polypeptides)IBA
11/2012 - 11/2000
2Amyloid (Amyloid Fibrils)IBA
11/2012 - 09/2011
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2008 - 07/2000
2Ethanol (Ethyl Alcohol)IBA
05/2008 - 09/2001
2Phorbol EstersIBA
11/2001 - 11/2000
2Biological ProductsIBA
10/2001 - 11/2000
2Protein Kinase CIBA
03/2001 - 11/2000
2indolactam VIBA
03/2001 - 09/2000
1von Willebrand FactorIBA
04/2014
1salicylhydroxamic acid (SHAM)IBA
04/2014
1Saline SolutionIBA
04/2014
1SiliconesIBA
04/2014
1cyclopropapyrroloindoleIBA
11/2010
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2008
1RimonabantIBA
01/2008
1Amantadine (Aman)FDA LinkGeneric
01/2008
1CannabinoidsIBA
01/2008
1Haloperidol (Haldol)FDA LinkGeneric
01/2008
1Methoxydimethyltryptamines (Methoxydimethyltryptamine)IBA
01/2008
1Serotonin ReceptorsIBA
01/2008
1Serotonin (5 Hydroxytryptamine)IBA
01/2008
1Dronabinol (THC)FDA LinkGeneric
01/2008
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2008
1N-Methylaspartate (NMDA)IBA
01/2008
1Dizocilpine Maleate (Dizocilpine)IBA
01/2008
1Serotonin AgentsIBA
01/2008
1Glutamic Acid (Glutamate)FDA Link
01/2008
1Amyloid beta-PeptidesIBA
10/2007
1Diacylglycerol KinaseIBA
11/2001
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
10/2001
1Proteins (Proteins, Gene)FDA Link
10/2001
1Therapeutic UsesIBA
09/2001
1Pharmaceutical PreparationsIBA
07/2001
1Interferon-alpha (Interferon Alfa)IBA
05/2001
1Cholecalciferol (Vitamin D3)FDA Link
04/2001
1Vitamin K 2 (Vitamin K2)IBA
04/2001
1HydrogenIBA
03/2001
1AmidesIBA
03/2001
1LactonesIBA
03/2001
12-nitrophenylpyruvic acidIBA
03/2001
1Protons (Proton)IBA
12/2000
1phorbolIBA
11/2000
1Phorbol 12,13-DibutyrateIBA
11/2000
1Superoxides (Superoxide)IBA
11/2000
1Epstein-Barr virus early antigenIBA
11/2000
1Tretinoin (Retinoic Acid)FDA LinkGeneric
10/2000
114-3-3 Proteins (14-3-3 Protein)IBA
10/2000
1Protein Isoforms (Isoforms)IBA
10/2000
1ThioamidesIBA
09/2000
1IsoenzymesIBA
09/2000
1Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
09/2000
1Coloring Agents (Dyes)IBA
07/2000
1Bicarbonates (Hydrogen Carbonate)IBA
07/2000
1AntibodiesIBA
07/2000
1ONO 4007IBA
07/2000
1Oxygen (Dioxygen)IBA
07/2000
1Diphenhydramine (Benadryl)FDA LinkGeneric
07/2000
1Lactic Acid (Lactate)FDA LinkGeneric
07/2000
1Indomethacin (Indometacin)FDA LinkGeneric
07/2000
1InterferonsIBA
01/2000

Therapy/Procedure

4Ligation
04/2013 - 05/2008
4Therapeutics
03/2003 - 01/2000
2Drug Therapy (Chemotherapy)
07/2001 - 02/2000
1Denervation
05/2006
1Stents
09/2003
1Endovascular Procedures
09/2002
1Subcutaneous Injections
07/2000